Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VCAM1 P19320 vascular cell adhesion molecule 1 0.80 0.422 0.808
TREM1 Q9NP99 triggering receptor expressed on myeloid cells 1 6.3E-03 0.515 0.808
TNFSF14 O43557 TNF superfamily member 14 Signaling 5.2E-02 0.529 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR9 Q9NR96 toll like receptor 9 9.8E-06 0.411 0.885
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SMPD1 P17405 sphingomyelin phosphodiesterase 1 Enzyme 3.9E-10 0.499 0.885
SLCO2B1 O94956 solute carrier organic anion transporter family member 2B1 Transporter 1.1E-05 0.653 0.500
SIRT6 Q8N6T7 sirtuin 6 Epigenetic regulator 3.9E-02 0.496 0.846
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
SFTPD P35247 surfactant protein D Surfactant 7.5E-05 0.500 0.846
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SELP P16109 selectin P 5.0E-32 0.460 0.769
SELE P16581 selectin E 7.9E-10 0.447 0.808
SCP2 P22307 sterol carrier protein 2 8.7E-07 0.644 0.500
S100A8 P05109 S100 calcium binding protein A8 Calcium-binding protein 0.14 0.430 0.962
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RARRES2 Q99969 retinoic acid receptor responder 2 2.7E-05 0.519 0.731
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PRKAB1 Q9Y478 protein kinase AMP-activated non-catalytic subunit beta 1 Kinase 5.3E-03 0.460 0.846